多个实例学习（MIL）方法在数字病理学中对GIGA像素大小的全型图像（WSI）进行分类变得越来越流行。大多数MIL方法通过处理所有组织斑块，以单个WSI放大倍率运行。这样的公式诱导了高计算要求，并将WSI级表示的上下文化限制为单个量表。一些MIL方法扩展到多个量表，但在计算上要求更高。在本文中，受病理诊断过程的启发，我们提出了Zoommil，该方法学会了以端到端的方式执行多层缩放。Zoommil通过从多个增强元中汇总组织信息来构建WSI表示。所提出的方法在两个大数据集上的WSI分类中优于最先进的MIL方法，同时大大降低了关于浮点操作（FLOPS）和处理时间的计算需求，最高为40倍。

乳腺癌是最常见的癌症，并寄存癌症的妇女的最多死亡人数。结合大规模筛查政策的诊断活动的最新进展显着降低了乳腺癌患者的死亡率。然而，病理学家手动检查病理学家的载玻片是麻烦的，耗时的，并且受到显着的和观察者内的变异性。最近，全幻灯片扫描系统的出现授权了病理幻灯片的快速数字化，并启用了开发数字工作流程。这些进步进一步使利用人工智能（AI）来协助，自动化和增强病理诊断。但是AI技术，尤其是深度学习（DL），需要大量的高质量注释数据来学习。构建此类任务特定的数据集造成了几个挑战，例如数据获取级别约束，耗时和昂贵的注释，以及私人信息的匿名化。在本文中，我们介绍了乳腺癌亚型（BRACS）DataSet，一个大队列的注释血清杂环蛋白和eosin（H＆E） - 染色的图像，以促进乳房病变的表征。 BRACS包含547个全幻灯片图像（WSIS），并从WSI中提取4539个兴趣区域（ROI）。每个WSI和各自的ROI都是通过三个董事会认证的病理学家的共识注释为不同的病变类别。具体而言，Bracs包括三种病变类型，即良性，恶性和非典型，其进一步亚级分为七个类别。据我们所知，这是WSI和ROI水平的最大的乳腺癌亚型的附带数据集。此外，通过包括被升值的非典型病变，Bracs提供了利用AI更好地理解其特征的独特机会。

Neural networks are prone to catastrophic forgetting when trained incrementally on different tasks. Popular incremental learning methods mitigate such forgetting by retaining a subset of previously seen samples and replaying them during the training on subsequent tasks. However, this is not always possible, e.g., due to data protection regulations. In such restricted scenarios, one can employ generative models to replay either artificial images or hidden features to a classifier. In this work, we propose Genifer (GENeratIve FEature-driven image Replay), where a generative model is trained to replay images that must induce the same hidden features as real samples when they are passed through the classifier. Our technique therefore incorporates the benefits of both image and feature replay, i.e.: (1) unlike conventional image replay, our generative model explicitly learns the distribution of features that are relevant for classification; (2) in contrast to feature replay, our entire classifier remains trainable; and (3) we can leverage image-space augmentations, which increase distillation performance while also mitigating overfitting during the training of the generative model. We show that Genifer substantially outperforms the previous state of the art for various settings on the CIFAR-100 and CUB-200 datasets.

Many challenging reinforcement learning (RL) problems require designing a distribution of tasks that can be applied to train effective policies. This distribution of tasks can be specified by the curriculum. A curriculum is meant to improve the results of learning and accelerate it. We introduce Success Induced Task Prioritization (SITP), a framework for automatic curriculum learning, where a task sequence is created based on the success rate of each task. In this setting, each task is an algorithmically created environment instance with a unique configuration. The algorithm selects the order of tasks that provide the fastest learning for agents. The probability of selecting any of the tasks for the next stage of learning is determined by evaluating its performance score in previous stages. Experiments were carried out in the Partially Observable Grid Environment for Multiple Agents (POGEMA) and Procgen benchmark. We demonstrate that SITP matches or surpasses the results of other curriculum design methods. Our method can be implemented with handful of minor modifications to any standard RL framework and provides useful prioritization with minimal computational overhead.

This paper presents a solution to the GenChal 2022 shared task dedicated to feedback comment generation for writing learning. In terms of this task given a text with an error and a span of the error, a system generates an explanatory note that helps the writer (language learner) to improve their writing skills. Our solution is based on fine-tuning the T5 model on the initial dataset augmented according to syntactical dependencies of the words located within indicated error span. The solution of our team "nigula" obtained second place according to manual evaluation by the organizers.

The task of reconstructing 3D human motion has wideranging applications. The gold standard Motion capture (MoCap) systems are accurate but inaccessible to the general public due to their cost, hardware and space constraints. In contrast, monocular human mesh recovery (HMR) methods are much more accessible than MoCap as they take single-view videos as inputs. Replacing the multi-view Mo- Cap systems with a monocular HMR method would break the current barriers to collecting accurate 3D motion thus making exciting applications like motion analysis and motiondriven animation accessible to the general public. However, performance of existing HMR methods degrade when the video contains challenging and dynamic motion that is not in existing MoCap datasets used for training. This reduces its appeal as dynamic motion is frequently the target in 3D motion recovery in the aforementioned applications. Our study aims to bridge the gap between monocular HMR and multi-view MoCap systems by leveraging information shared across multiple video instances of the same action. We introduce the Neural Motion (NeMo) field. It is optimized to represent the underlying 3D motions across a set of videos of the same action. Empirically, we show that NeMo can recover 3D motion in sports using videos from the Penn Action dataset, where NeMo outperforms existing HMR methods in terms of 2D keypoint detection. To further validate NeMo using 3D metrics, we collected a small MoCap dataset mimicking actions in Penn Action,and show that NeMo achieves better 3D reconstruction compared to various baselines.

Model calibration, which is concerned with how frequently the model predicts correctly, not only plays a vital part in statistical model design, but also has substantial practical applications, such as optimal decision-making in the real world. However, it has been discovered that modern deep neural networks are generally poorly calibrated due to the overestimation (or underestimation) of predictive confidence, which is closely related to overfitting. In this paper, we propose Annealing Double-Head, a simple-to-implement but highly effective architecture for calibrating the DNN during training. To be precise, we construct an additional calibration head-a shallow neural network that typically has one latent layer-on top of the last latent layer in the normal model to map the logits to the aligned confidence. Furthermore, a simple Annealing technique that dynamically scales the logits by calibration head in training procedure is developed to improve its performance. Under both the in-distribution and distributional shift circumstances, we exhaustively evaluate our Annealing Double-Head architecture on multiple pairs of contemporary DNN architectures and vision and speech datasets. We demonstrate that our method achieves state-of-the-art model calibration performance without post-processing while simultaneously providing comparable predictive accuracy in comparison to other recently proposed calibration methods on a range of learning tasks.

Dense prediction tasks such as segmentation and detection of pathological entities hold crucial clinical value in the digital pathology workflow. However, obtaining dense annotations on large cohorts is usually tedious and expensive. Contrastive learning (CL) is thus often employed to leverage large volumes of unlabeled data to pre-train the backbone network. To boost CL for dense prediction, some studies have proposed variations of dense matching objectives in pre-training. However, our analysis shows that employing existing dense matching strategies on histopathology images enforces invariance among incorrect pairs of dense features and, thus, is imprecise. To address this, we propose a precise location-based matching mechanism that utilizes the overlapping information between geometric transformations to precisely match regions in two augmentations. Extensive experiments on two pretraining datasets (TCGA-BRCA, NCT-CRC-HE) and three downstream datasets (GlaS, CRAG, BCSS) highlight the superiority of our method in semantic and instance segmentation tasks. Our method outperforms previous dense matching methods by up to 7.2 % in average precision for detection and 5.6 % in average precision for instance segmentation tasks. Additionally, by using our matching mechanism in the three popular contrastive learning frameworks, MoCo-v2, VICRegL and ConCL, the average precision in detection is improved by 0.7 % to 5.2 % and the average precision in segmentation is improved by 0.7 % to 4.0 %, demonstrating its generalizability.

Modal verbs, such as "can", "may", and "must", are commonly used in daily communication to convey the speaker's perspective related to the likelihood and/or mode of the proposition. They can differ greatly in meaning depending on how they're used and the context of a sentence (e.g. "They 'must' help each other out." vs. "They 'must' have helped each other out.") Despite their practical importance in natural language understanding, linguists have yet to agree on a single, prominent framework for the categorization of modal verb senses. This lack of agreement stems from high degrees of flexibility and polysemy from the modal verbs, making it more difficult for researchers to incorporate insights from this family of words into their work. This work presents Moverb dataset, which consists of 27,240 annotations of modal verb senses over 4,540 utterances containing one or more sentences from social conversations. Each utterance is annotated by three annotators using two different theoretical frameworks (i.e., Quirk and Palmer) of modal verb senses. We observe that both frameworks have similar inter-annotator agreements, despite having different numbers of sense types (8 for Quirk and 3 for Palmer). With the RoBERTa-based classifiers fine-tuned on \dataset, we achieve F1 scores of 82.2 and 78.3 on Quirk and Palmer, respectively, showing that modal verb sense disambiguation is not a trivial task. Our dataset will be publicly available with our final version.

Relation extraction (RE) is a sub-discipline of information extraction (IE) which focuses on the prediction of a relational predicate from a natural-language input unit (such as a sentence, a clause, or even a short paragraph consisting of multiple sentences and/or clauses). Together with named-entity recognition (NER) and disambiguation (NED), RE forms the basis for many advanced IE tasks such as knowledge-base (KB) population and verification. In this work, we explore how recent approaches for open information extraction (OpenIE) may help to improve the task of RE by encoding structured information about the sentences' principal units, such as subjects, objects, verbal phrases, and adverbials, into various forms of vectorized (and hence unstructured) representations of the sentences. Our main conjecture is that the decomposition of long and possibly convoluted sentences into multiple smaller clauses via OpenIE even helps to fine-tune context-sensitive language models such as BERT (and its plethora of variants) for RE. Our experiments over two annotated corpora, KnowledgeNet and FewRel, demonstrate the improved accuracy of our enriched models compared to existing RE approaches. Our best results reach 92% and 71% of F1 score for KnowledgeNet and FewRel, respectively, proving the effectiveness of our approach on competitive benchmarks.